Episodes
Thursday Dec 26, 2024
The Canine Gut Microbiome and Antibiotic Resistance (Zhou 2024)
Thursday Dec 26, 2024
Thursday Dec 26, 2024
In this episode, we delve into the intriguing world of dog microbiomes, exploring how lifestyle choices impact these gut ecosystems in pets, rural, and stray dogs. Discover how these differences translate into varying levels of antibiotic-resistant genes (ARGs) across dog groups and the potential implications for humans.
Learn about the dominant bacteria phyla present in dogs and the unexpected higher abundance of ARGs found in pet dogs. Find out why the presence of the MCR1 gene, known for conferring resistance to last-resort antibiotics, raises alarm bells for both pet dog health and potential transmission to humans.
The episode also sheds light on the role of mobile genetic elements (MGEs) in spreading these ARGs and introduces the Risk of Antibiotic Resistance and Pathogenicity Score used to assess the risk posed by dogs' microbiomes. With fascinating insights into the specific bacteria and their impacts, this episode underscores the importance of responsible antibiotic use and hints at exciting future possibilities for breeding healthier dogs.
(Zhou et al Metagenomic insights into the resistome, mobilome, and virulome of dogs with diverse lifestyles. Animal Microbiome (2024) 6:76)
Download pdf:
https://animalmicrobiome.biomedcentral.com/articles/10.1186/s42523-024-00364-x
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